EBIO 1030 Lecture 7: intro to ebio notes oct 16
Document Summary
Gene expression- the process by which dna directs protein synthesis. Contains uracil (u) instead of thymine (t) Rna is also a polymer of nucleotides. The rna nucleotides are converted into amino acids (different languages=translation) This makes a protein which is a polymer of amino acids. Using the info in dna to make a complementary rna strand. One gene is transcribed into one mrna strand. Rna polymerase separates the dna strands and joins the rna nucleotides together. The rna is complementary to the dna template strand. Follows same base pairing rules as dna except that uracil substitutes for thymine. Initiation occurs when rna polymerase binds dna sequences called promoters. In eukaryotes rna polymerase cannot bind a. Other proteins called transcription factors must bind the promoter first. Elongation occurs as rna polymerase moves along dna strand and synthesizes the pre-mrna transcript. Termination occurs when rna polymerase, dna and the rna transcript dissociate. A sequence of nucleotides indicates where rna should end.