EBIO 1210 Lecture Notes - Lecture 11: Dihybrid Cross, Neurofibromatosis, Epistasis
7 Dec 2017
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Document Summary
The foundation for the science of genetics was laid in 1860s, when gregor mendel used varieties of peas to conduct experiments on inheritance. Gregor mendel was a monk with scientific training in mathematics, physics, and biology. One of his great legacies was proposing and demonstrating that the characteristics of organisms are inherited in, or as, discreet units (particulate inheritance) from their parents. His theory was ignored, until the turn of the twentieth century, perhaps because his biological peers were not accustomed to reviewing quantitative or mathematical data. Even darwin, whose evolutionary theory rests on genetic variation among individuals, failed to understand mendel"s point and relied on the blending hypothesis, which was quite popular for most of the 19th century. Some other popular concepts of inheritance include: preformation, pangenesis, inheritance of acquired characteristics (too much given to action, blending hypothesis (not accurate because not blending" but two different alleles.
