MCDB 1150 Lecture Notes - Lecture 12: Calmodulin, Membrane Protein, Cell Nucleus
17 Nov 2016
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Protein structure and how it could change. Prion proteins cns (central nervous system) When you have more than one polypeptide forming a protein. Hemoglobin; 2 alpha and 2 beta (individual polypeptides) Learning goals, nucleic acids - on d2l. Clicker question: the function of nucleotides in the cell is . To provide energy for the cellular process. To provide building blocks for nucleic acids. First carbon is where the base is covalently attached. Incoming nucleotides are added at the third carbon. Fourth carbon is involved in ring closure. Fifth carbon - phosphate is covalently bound. Pyrimidines (longer name, shorter dna) vs. purines (shorter name, longer. Ribonucleotide (2 oh) vs. deoxyribonucleotide (lacking group) The addition of phosphate groups raises the potential energy of the monomer. Energy is released when phosphates are removed from hydrolysis. 3" and 5" carbons joined by phosphodiester linkage. 3" hydroxyl - new nucleotides are added here. Rna can form bases form base pairs within a single strand.
