BIO 122 Lecture Notes - Lecture 5: Adherens Junction, Tight Junction, Intermediate Filament
30 May 2018
School
Department
Course
Professor
Prior to Week 5 Class 2 Chapter 11 –Cell to Cell Interactions
Know
• The general types of junctions that can occur between cells or between cells and matrix (i.e., anchoring
junctions), and their basic functions
o tight junctions between adjacent cells
▪ water tight seal
o gap junctions between adjacent cells
▪ channels to allow small molecules through animal cells
o adherens junctions
▪ link actin filaments between adjacent cells
▪ that cadherins are an example
o desmosomes
▪ link intermediate filaments between adjacent cells
o integrins
▪ link intracellular actin filaments to the extracellular matrix
o plasmodesmata
▪ gaps in plant cell wall to allow molecules through
o middle lamella
▪ attachment between 2 plant cell walls
• What basal refers to
o bottom
• What luminal refers to
o cavity
Understand
• The role of ECM in tissue function in regard to tension and compression
o Bears the tension and compression
• The interaction between the ECM and cells is critical for tissues to function
• Why cell communication is necessary
o Allow cells to function as a whole in tissue
• What gap junctions are, and how they are involved in signaling
o Allow small molecules to pass through animal cells
• What allows different cells to respond differently to the same signals
o Different receptors
• That the arrangement of junctions can be different in different tissues and why attachments are selective
o Depends on the specific function of the cell
• Why tight junctions are important in epithelial tissues
o Allow skin to be a waterproof seal
o Keep cells close together
• That cells are polar and that different proteins will be expressed on different sides of a given cell and why
find more resources at oneclass.com
find more resources at oneclass.com
