BIO 203 Lecture Notes - Lecture 1: Reabsorption, Nephrin, Basal Lamina
10 Aug 2016
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Document Summary
Most important fxn of the kidney is the homeostatic regulation of water and ion content in the blood: regulation of extracellular fluid (ecf) volume and blood pressure. Ecf vol decrease, blood pressure decreases and body cannot maintain adequate blood flow: regulation of osmolarity, maintenance of ion balance. Kidneys keep concentration of key ions within normal range. Na major ion involved in regulation of ecf vol and osmolarity: homeostatic regulation of ph. If too acidic, kidneys remove h+ and conserve hco3 and vice versa when too basic: excretion of wastes. Urobilinogen gives urine its yellow color: production of hormones. Kidneys synthesize erythropoietin, the cytokine/hormone that regulates red blood cell synthesis. Also synthesize renin, an enzyme that regulates the production of hormones involved in na balance and blood pressure homeostasis. Urinary system consists of kidneys, ureters, bladder, and urethra. Water and solutes move from plasma into hollow tubules (nephrons) that make up the bulk of the kidneys.
