BIO 203 Lecture Notes - Lecture 1: Skeletal Muscle, Logarithmic Scale, Muscarinic Acetylcholine Receptor
10 Aug 2016
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Electrophys: transmembrane forces and flows- how you get nerve and muscle signals. Nerve signal involves ions moving across a membrane (which doesn"t happen easily) so will involve protein (ion channels: concentrate on ions here. Depends on strength of voltage field (faraday constant, valence on an ion). If we have semi-permeable membrane and diff concentrations of solutes on 2 sides, tends to suck water across membrane. That can build up a pressure difference (2). Can use applied force to push it back and balance(3). But if you have a difference in concentration (like glucose), if it doesn"t get across very well*: some solutes that can get across and some cant- impermeant ions. Cell has n ions (non), stick it in isosmotic (same total solute concentration) throw that cell in there- not pulling water across membrane because total solute concentrations about the same.
