NFS 230 Lecture Notes - Lecture 11: Retinol Binding Protein, Vitamin A Deficiency, Beta-Carotene
15 Nov 2016
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Document Summary
Fat soluble vitamin w/ the biological activity of retinol. Vision and converts retinol to retinoic acid. Conversion of retinol to retinal is reversible; conversion of retinal to retinoic acid is irreversible. Absorbed in the lymph system, stored to liver and then carried to the blood via retinol binding protein (rbp) The precursor for vitamin a and antioxidant. A carotenoid w/ vitamin a activity that is split to form retinol in the liver or intestine. Vitamin a roles: promote vision, protein synthesis and cell differentiation to maintain health of epithelial tissue and skin, support reproduction and regulate growth immunity. Converts light energy to nerve impulses in the retina. Retina have rhodopsin (light sensitive pigment w/ retinal and the protein opsin) Light passes through cornea, strikes retina, rhodopsin responds. The opsin is released and retinal shifts to trans, making an electrical impulse to convey a message to the brain.
