BIOLOGY 202L Lecture Notes - Lecture 24: Genetic Predisposition, Heritability, Genetic Variation

• School: Duke University
• Department: Biology
• Course: BIOLOGY 202L
• Professor: John Willis

Document Summary

Now we will consider change in a complex quantitative (polygenic) traits. Develop ways of predicting trait (phenotypic) evolution due to selection. Describing population variation and evolution (see written graph) Evolution in terms of trait mean over time. Greater potential for change in trait mean when greater genetic variation trait. Genetic predisposition is not the only factor involved in phenotypic variance between parents and offspring: h2 = vg/vp = total genetic variance / total phenotypic variance = broad-sense. Coefficient of genetic determination heritability : issue of nature vs nurture , requirements: specific population specific time specific environment. Narrow sense heritability: measure of similarity between relatives in a sexual/outcrossing species, h2 = slope of regression of graph (kids" trait vs parents" trait) = narrow-sense heritability . 0 < m < 1, then some degree of correlation (direct)? in reality, could be negative if we placed parents in poor environment and offspring in good environment.