BIOLOGY 154 Lecture Notes - Lecture 5: Antibody, T Cell, Blood Transfusion

188 views4 pages
15 Sep 2016
Department
5 Koch’s Postulates
Robert Koch
1860s Germany
studied pathogens
examine blood of animals who died of anthrax
caused by bacteria
noticed that rods were absent from blood of healthy animals
comparison / control group correlation
what role do those rods play in disease causation?
wanted to transfer rods to healthy mice to see effect
transferred blood of animal that died of anthrax with a splinter and mouse died next day
dead mouse filled with rods, only a few transferred
suggests that rods grow
created in vitro culture system to watch rods grow and repeated many times
start with correlation and try identify the agent of causation
Koch’s Postulates
1. Pathogen present in all diseased individuals and not present in healthy ones
2. Pathogens can be isolated from host and grown in culture
3. If inoculate isolated pathogen into a healthy host, then should cause disease
4. Reisolate microbe from experimental infection
Issues
find more resources at oneclass.com
find more resources at oneclass.com
Unlock document

This preview shows page 1 of the document.
Unlock all 4 pages and 3 million more documents.

Already have an account? Log in

Get OneClass Notes+

Unlimited access to class notes and textbook notes.

YearlyBest Value
75% OFF
$8 USD/m
Monthly
$30 USD/m
You will be charged $96 USD upfront and auto renewed at the end of each cycle. You may cancel anytime under Payment Settings. For more information, see our Terms and Privacy.
Payments are encrypted using 256-bit SSL. Powered by Stripe.