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Class Notes for BIOLOGY 202L at Duke University

DUKEBIOLOGY 202LJohn WillisFall

BIOLOGY 202L Lecture Notes - Lecture 22: Reverse Transcriptase, Opsin, Nucleotide Diversity

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Snp/marker alleles near adaptive allele (0 to low recombination) hitchhike : reduction in pi, no/low nucleotide diversity indicates recent evolution. I
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DUKEBIOLOGY 202LJohn WillisFall

BIOLOGY 202L Lecture Notes - Lecture 20: Blood Sugar, Lactase, Lactose Intolerance

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Appx 10,000 y/a people began to domesticate animals, live together, cultivate crops. Almost everyone can digest milk as babies but not necessarily as a
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DUKEBIOLOGY 202LJohn WillisFall

BIOLOGY 202L Lecture Notes - Lecture 12: Chromosome, Petal, Delaware Route 3

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Focusing on differentiation due to differences in alleles in loci. Complex/polygenic/quantitative traits: traits which vary within a species due to dif
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DUKEBIOLOGY 202LJohn WillisFall

BIOLOGY 202L Lecture 19: Bio 202 Review SUNDAY NIGHT and monday

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>1 amino acid changes are from positive selection. <<1 purifying selection to delete the bad mutations: typical. = 1 no selection on the protein: chang
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DUKEBIOLOGY 202LJohn WillisFall

BIOLOGY 202L Lecture 10: Bio 202 Lecture

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DUKEBIOLOGY 202LJohn WillisFall

BIOLOGY 202L Lecture Notes - Lecture 23: Lactase, Haplotype, Tibetan Plateau

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East (or south) africa spread throughout africa migrated outward to colonize the. Everyone with lactase persistence has a similar sequence surrounding
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DUKEBIOLOGY 202LJohn WillisFall

BIOLOGY 202L Lecture Notes - Lecture 25: Genetic Linkage, Heritability, Statistical Power

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Look for natural selection in regions of decreased variability with the principle of selective. See that human evolution hasn"t undergone many recent s
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DUKEBIOLOGY 202LJohn WillisFall

BIOLOGY 202L Lecture Notes - Lecture 12: Allele Frequency, Haplotype, Genetic Diversity

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Two populations: one is fixed for one, one is fixed for the other allele random mating = Nucleotide diversity: measure of diversity given dna sequences
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DUKEBIOLOGY 202LJohn WillisFall

BIOLOGY 202L Lecture Notes - Lecture 9: Meiosis, Chromosome, Centimorgan

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When loci are on the same chromosome, either : no recombinants because they are so close, at least 1 crossover because the loci are far apart. Two trai
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DUKEBIOLOGY 202LJohn WillisFall

BIOLOGY 202L Lecture Notes - Lecture 4: Adaptive Mutation, Chromosome, Cytokinesis

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Clearly evolution via natural selection depends on genetic differences among individuals in a population species. Origin of replication attaches to cel
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DUKEBIOLOGY 202LJohn WillisFall

BIOLOGY 202L Lecture Notes - Lecture 5: Alpha Cell, Meiosis, Chromosome

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At molecular level, many genes are synonymous throughout. Core of genetics: what happens to chromosomes during meiosis: fusion/mating = complication/hi
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DUKEBIOLOGY 202LJohn WillisFall

BIOLOGY 202L Lecture Notes - Lecture 18: Selective Breeding, Molecular Clock, Zygote

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Parent vs offspring graphs: slope = h2, scatter plot of midparent (avg phenotype) vs avg offspring phenotype. Heritability: variation due to genetic fa
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