BIOLOGY 290 Lecture Notes - Lecture 14: Measles, Leprosy, Autoimmunity
Document Summary
Bio 209 10/18, intro lecture on humans as resources. Microparasites: small, like a virus, not visible by eye, smaller genome reproduce within the host infect host cells, usually number of infectious parasites is not quantified; just infected vs. not infected. Host transmission heterogeneity: not everyone spreads a disease equally/to the same number of people; ex: typhoid mary a cook who contaminated a lot of food causing exposure. Host population size: how does human/host pop size impact infectious disease. Autoimmunity: people more likely to get lupus are less susceptible to hiv (hiv uses some of bodies own immunity mechanisms, so since this is a problem in people who get lupus, hiv is not as communicable) Driving pathogen evolution: flu immunity conferred through vaccinations and past infections; this pushes the flu to evolve a lot. Key concepts: epidemic growth and the epidemic curve.