NEUROSCI 101 Lecture Notes - Lecture 5: Neocortex, Donepezil, Cupcake

• School: Duke University
• Department: Neuroscience
• Course: NEUROSCI 101
• Professor: Williams

Document Summary

I trained a rat for several days to learn to find a platform in a water maze task until it was very good at the task, then i gave the rat 2 days off from training. Since the nmda receptor is responsible for learning, the rat has already learned the location of the platform. Blocking the nmda receptors in the hippocampus will deplete long-term knowledge, but won"t affect the rat"s ability to locate the platform since it"s old knowledge. Correlational observations - time course of ltp similar for memory formation. Somatic interventions - pharmacological treatments that block ltp impair learning. Behavioral interventions - training an animal in a memory task can induce ltp. Implicit/nondeclarative memory - hm could still be primed (neocortex) or classical conditioning (amygdala, cerebellum) Working memory - very short time, could repeat back stream of digits. Procedural memory - hm could still perform the mirror-tracing task after learning.