NEUROSCI 101 Lecture Notes - Lecture 4: Neurotransmitter Receptor, Neuromuscular Junction, Signal Generator

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Each neuron synthesizes and releases only one neurotransmitter. F, neurons can release multiple types of nts. Dopamine can trigger either an ipsp/epsp depending on what receptor its binding to. If you blocked ca2+ at the end of the axon, more neurotransmitters would be released. F, need ca uptake for vesicles to release nts into the synapse since the depolarization of the neuron cell will open the ca2+ gates and stimulate the release of nts from vesicles. Glutamate is the neurotransmitter used in the peripheral nervous system at every neuromuscular junction. Ionotropic receptor, which leads to direct opening of ion channels but is shorter acting, explaining the rapid stimulation. Record the epsp with a recording electrode to record the baseline. Give a pulse burst, a high frequency stimulation with an electrode. Give the same pulse at the time of the pre-tetanus. Glutamate binds to the receptor, na+ flows in, depolarizes the cell.

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