BIOSC-101 Lecture Notes - Lecture 15: Acetyl-Coa, Electrochemical Gradient, Blood Transfusion
26 Aug 2020
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Glycolipids: membrane lipid may have carbohydrate chains in the exoplasmic domain. Example: abo blood antigens oligosaccharide chains covalently attached to glycolipids (or glycoproteins) in the plasma membrane of red blood cell"s (rbc) Glycosyltransferases that act galactose or n-acetylgalactosamine (galnac) to the o antigen determines the blood type. Blood transfusion with incorrect blood type causes the immune system to produce anti-bodies against the missing antigen and leads to destruction of. Made from two carbon building block (acetate) Phospholipid precursors bind with water soluble coa to form acetyl coa or fatty. They are assembled by enzymes on cytoplasmic face of smooth er membrane acid binding protein (fabp) for transport through cytoplasm which link fatty acyl coas glycerol 3-phosphate and polar head precursors. Fippase: integral mp"s that facilitate transport of phospholipid from one face of a membrane to another. Cholesterol: synthesized in the liver and utilizes ga as a carrier in the cytosol and has a catalytic enzyme bound to the er membrane.
