ANT 333 Lecture Notes - Lecture 1: Hepatomegaly, Shortness Of Breath, Schistosomiasis
24 Jan 2016
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Ant 333 schistosomiasis and other ntds lecture 1. Parasitic disease: infectious disease, complex life cycles, involves one or more hosts. 650 million people at risk in many countries. Significant morbidity: usually non-fatal but debilitating disease, liver or urinary tract problems. Hepatomegaly (enlarged liver): 8. 5 million in africa. = schistosomal cerceriae penetrate the skin after freshwater exposure and migrate via the lungs to the vessels of the bladder of gut. The worms: mircacidia hatch from an egg. Infect a snail, become sporocysts and reproduce asexually: cercaria are released into the water. Cercaria infect humans (or rats, dogs etc. ) by digesting their way through skin. They leave their tails at the skin and transform into. Schistosomula -> bloodstream: in the liver (bladder) male and female worms pair, becoming adult schistosomes. 1-2 days: small proportion experience swimmer"s itch . 3-8 weeks: kayama fever: fever, chills, headache: large liver, spleen, and lymph nodes, eosinophilia. 3 months to years: urinary disease haematuria, urinary symptoms.
