BIOL 205 Lecture Notes - Lecture 28: Portal Vein, Bile Canaliculus, Hepatic Veins

• School: Emory University
• Department: Biology
• Course: BIOL 205
• Professor: Starnes Amanda

Document Summary

Liver: 4 liver lobes in humans; right lobe is largest, all vertebrates have liver, embryonic origins : endodermally derived (mesoderm indirectly affects the proliferation of liver, macroscopic (handout) a. i. a. ii. Hexagonal arrangement with largest blood vessel (central vein) in the middle that associates with each lobule a. iii. a. ii. a. iii. a. iv. bile canaliculi --> bile ductule --> . Portal triad : hepatic artery, hepatic portal vein, bile ductule a. i. 1. Hepatic portal vein --> sinusoids --> central vein --> heart : contains nutrients (polymers) to be distributed to rest of body) a. i. 2. Prothrombin + fibrinogen -- clotting function: pathology: cirrhosis a. i. Jaundice / icterus == yellowing of skin and eye (sclera - whites of eyes) a. a. i. Hyper == excess: excessive vitamin b3 -- niacin. Blood"s path (handout: hepatic artery and hepatic portal vein --> sinusoids --> central vein --> hepatic vein --> inferior vena cava, kupffer cells a. i. a. ii. Rbc -- live for 120 days and then broken down and recycled.