PSYC 210 Lecture Notes - Lecture 11: Prefrontal Cortex, Learned Helplessness, Posttraumatic Stress Disorder
19 May 2018
School
Department
Course
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PSYCH 210 – Adult Abnormal Psychology
Lecture 11
Learning Catalytic Question
According to your book, traumas caused by humans are more likely to cause PTSD than are
natural disasters.
o True
Decreased grey-matter volume of which brain area has been associated with both PTSD and
major depression?
o Hippocampus
What are some protective factors the book discussed that may help a person cope with severe
traumas in a more adaptive way (select all that apply)?
o High intelligence
o Strong social support
For Midterm
Know diagnostic criteria
Understand how diagnoses are made
Don’t need to memorize case study – understand concepts
Enhancing PTSD Treatment
D-Cycloserine – enhances the sensitivity of NMDA receptors, a key mechanism of long-term
potentiation (i.e., learning)
- Some efficacy supporting this
- CAPS score – PTSD symptoms severity
- DCS exposure → results after 6 months check in therapy had “taken hold” more
- Using virtual reality, it did work
Models of Resilience
- Steve mayer – looking at the role of perceived controllability in mediating role of
stressors
- 3 chamber paradigm – 2 rats where the tails have a loop around them to get a shock,
control rat is in the same set up but never gets shocked. The first rat can turn of the shock
for both rats. (escapable condition) but the second rat can’t do anything (inescapable
condition) even if he spins the wheel
- Different context around the same shock
- Inescapable rat develops a learned helplessness
- Critical role in medial prefrontal cortex
- Found that if stimulate mPFC for inescapable rat: Prevent helplessness
- If deactivate mPFC for escapable rat: Induce helplessness
- Provide exposure to escapable condition before inescapable condition: Prevent
helplessness
find more resources at oneclass.com
find more resources at oneclass.com
Document Summary
According to your book, traumas caused by humans are more likely to cause ptsd than are natural disasters: true. Decreased grey-matter volume of which brain area has been associated with both ptsd and major depression: hippocampus. What are some protective factors the book discussed that may help a person cope with severe traumas in a more adaptive way (select all that apply): high intelligence, strong social support. Don"t need to memorize case study understand concepts. D-cycloserine enhances the sensitivity of nmda receptors, a key mechanism of long-term potentiation (i. e. , learning) Dcs exposure results after 6 months check in therapy had taken hold more. Steve mayer looking at the role of perceived controllability in mediating role of stressors. 3 chamber paradigm 2 rats where the tails have a loop around them to get a shock, control rat is in the same set up but never gets shocked.
