PSYC 210 Lecture Notes - Lecture 13: Extrapyramidal Symptoms, Tardive Dyskinesia, Dissociative Identity Disorder
19 May 2018
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PSYCH 210 – Adult Abnormal Psychology
Lecture 13
Learning Catalytic Questions
Monkey sees a triangle and unexpectedly gets a squirt of juice in its mouth. Monkey's dopamine
neurons
o Have a burst
The abberant salience model of dopamine dysfunction in schizophrenia suggests that:
o Positive symptoms result from inappropriate firing of dopamine neurons to irrelevant or
neutral stimuli
What are the names of the different theories of the etiology of Dissociative Identity Disorder?
(select all that apply)
o Socio-cognitive model, posttraumatic model
What is believed to precipitate DID symptom presentation?
o Extreme childhood trauma or abuse
Schizophrenia Spectrum Part II – Lecture 13
Treatment of Schizophrenia
Two Broad Classes:
First-generation anti-psychotic medications (also called neuroleptics)
Second generation (or atypical) anti-psychotic medications – more typical and used now
- Thorazine first to be synthesized and used
- Haloperidol or Haldol is still used from the first generation drugs
- Most widely used is Olazapine
First-generation
- D2 receptor antagonists reduce positive symptoms; little effect on negative symptoms
- D2 receptors are distributed heavily in the striatum
- D1 and D5 are a family – function together – called D1 like
- D2, D3 and D4 are a family – called D2 like
- Prevents inappropriate dopamine release, also blocks normal dopamine release – so
message doesn’t get through, but message getting through is important for normal
pleasurable behavior
- Done experiments with rats, if give rat Haldol – block dopamine, worsen motivation
impairments, rats don’t care much for work aren’t that motivated
Side effects
- With prolonged use, they mimic neurological disease
- Extrapyramidal side effects
- Tardive dyskinesia
find more resources at oneclass.com
find more resources at oneclass.com
Document Summary
Monkey sees a triangle and unexpectedly gets a squirt of juice in its mouth. The abberant salience model of dopamine dysfunction in schizophrenia suggests that: positive symptoms result from inappropriate firing of dopamine neurons to irrelevant or neutral stimuli. What are the names of the different theories of the etiology of dissociative identity disorder? (select all that apply: socio-cognitive model, posttraumatic model. What is believed to precipitate did symptom presentation: extreme childhood trauma or abuse. Second generation (or atypical) anti-psychotic medications more typical and used now. Thorazine first to be synthesized and used. Haloperidol or haldol is still used from the first generation drugs. D2 receptor antagonists reduce positive symptoms; little effect on negative symptoms. D2 receptors are distributed heavily in the striatum. D1 and d5 are a family function together called d1 like. D2, d3 and d4 are a family called d2 like.
