PSYC 323 Lecture Notes - Lecture 1: Animal Locomotion, Peritoneum, Nicotine

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Effe(cid:272)t(cid:863)(cid:895: vehicles of a drug (major ways of getting a drug into a fluid so that it can be injected, water. Inhalation/pulmonary: breathing into the lungs: e. g. nicotine, which enters lung tissue when you smoke, general somatic injections: Intravenous (iv): directly into vein: called (cid:862)(cid:373)ai(cid:374)li(cid:374)i(cid:374)g(cid:863) i(cid:374) drug culture. Intramuscular (im): into a muscle: this kills muscle cells permanently, subcutaneous (sc): under the skin. Inside of the cavity which contains your suspended intestines: parenteral routes specific to the nervous system (examples in rats): If a drug activates the receptor (e. g. by mimicking a neurotransmitter), the drug is a(cid:374) (cid:862)ago(cid:374)ist(cid:863) Increased dose strengthens the effect until a certain point at which the effect plateaus: example of amphetamine, locomotor activity will progressively increase as you go up the curve. In other words, it makes it so that more of the agonist is required to produce a given effect: narcan is an example of an antagonist; heroin (opiate) is agonist.

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