PSB 3002 Lecture Notes - Lecture 21: Indirect Agonist, Anxiolytic, Apoptosis

41 views3 pages
23 Mar 2018
School
Department
Course

Document Summary

Withdrawal effects are not the cause of addiction; the abuse potential of a drug is related to its ability to reinforce drug-taking behavior. Know the experiment in which addictive behavior is suppressed by a lesion and drug administration. Combined lesion of nac and dopamine antagonist in dorsal striatum suppresses addictive behavior. Understand negative reinforcement (not the same as a punishing stimulus from instrumental conditioning!) Removal or reduction of aversive stimulus that is contingent on particular response. This is not the same as a punishing reinforcer. Aversive stimulus can be withdrawal symptoms or anxiety that is relieved by taking drug. Understand the specific actions of alcohol on different neurotransmitter receptors, especially those that cause cell death/apoptosis. --interferes with transmission of glutamate at nmda receptors. Low doses produce mild euphoria and anxiolytic effect and reduces discomfort of anxiety. Negative reinforcement is through termination of aversive stimulus. Increases activity of dopaminergic neurons of mesolimbic system and increases release of dopamine in.

Get access

Grade+20% off
$8 USD/m$10 USD/m
Billed $96 USD annually
Grade+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
40 Verified Answers
Class+
$8 USD/m
Billed $96 USD annually
Class+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
30 Verified Answers

Related Documents