PSB 3002 Lecture Notes - Lecture 26: Myelin, Organ Transplantation, Caspase
Document Summary
--inability to remember events before brain damage occurred. - hippocampus is thought to link individual memories together to preserve order and sequence. The study of retrograde amnesia in patients with hippocampal damage indicated 3 main points; what are they? (hint: see slide 33, lecture 21) -- memories older than 15 year appear intact compared to controls. -- memory of events within 15 years of damage severely affected. -- suggests storage process takes 10-15 years and hippocampus needed to recall newer memories. An fmri study of the role of the hippocampus and cerebral cortex in long-- ter(cid:373) (cid:373)e(cid:373)ory storage indicated 3 main point: what are they? (hint: see slide 34, lecture 21) --fmri shows retrieval of youngest memories activated hippocampus most and cortex least. -- suggests initial storage in hippocampus followed by transfer to cortex. -- characterized by spongelike appearance of brain tissue. -most cases considered sporadic - rare occurrence, no obvious hereditary or infectious cause.