BSC 1010C Lecture Notes - Lecture 12: Quantitative Trait Locus, Pleiotropy, Sickle-Cell Disease

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12 Oct 2016
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Early plant biologists produced hybrids with puzzling results. True-breeding: said of a breed or variety of organism from one generation to the next. This is due to the genotypes that determine relevant traits being homozygous. Segregating: the process by which alternative forms of traits are expressed in offspring rather than blending each trait of the parents in the offspring. Mendel was the first to quantify the results of his crosses. Me(cid:374)del"s e(cid:454)peri(cid:373)e(cid:374)ts i(cid:374)(cid:448)ol(cid:448)ed re(cid:272)ipro(cid:272)al (cid:272)rosses (cid:271)et(cid:449)ee(cid:374) true-breeding pea varieties followed by one or more generations of self-fertilization. His mathematical analysis of experimental results led to the present model of inheritance. Monohybrid cross: cross that follows only two variations on a single trait, such as white- and purple- colored flowers. Me(cid:374)del"s 7 traits: flo(cid:449)er (cid:272)olor, seed (cid:272)olor, seed te(cid:454)ture, pod (cid:272)olor, pod shape, flo(cid:449)er position, and plant height. The f1 generation exhibits only one of two traits with no blending.

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