PCB 4232 Lecture Notes - Lecture 2: Pyroptosis, Infection, Low-Density Lipoprotein

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Pyroptosis 95% na ve t cell death in lymph nodes. Pyroptosis (leads to inflammation)(caspase-1 pore dependant: acute infection, clinically latent phase, aids. Case control study = you have the case (hiv infected) and control (non infected) Epidemiology = study of the distribution and determinants of health events, and a. These helped scientist show relationship between aids and # and frequency of sexual partners. Homosexuals had more chance of being infected. the application of this study to the control of disease. Hiv dies outside body, cant resist environmental pressures. Semen and blood remain major transferring substances of hiv. Highest method of transmission in united states = male to male sex. Most new cases were white m2m and black m2m. Women highest method of transmission = heterosexual sex. Most transmission = m2m sex (46%) then heterosexual transmission (39%) Women represent 20% of new diagnoses in united states. More than 90% of children who acquired hiv in 2011 live in sub saharan africa.

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