BSC-1005 Lecture Notes - Lecture 4: Abo Blood Group System, Mendelian Inheritance, Zygosity

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29 Nov 2017
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10-22-17: segregation deals with one trait (monohybrid) that are sent to different places, the dihybrid cross, each parent forms four genetically distinct gametes, ob average each type of gamete will be formed 1/4th of the time. 10-25-17: blue people of troublesome creek, the fugates had seven children, four had blue skin, tay sachs-disease found in people of ashkenazi descent 1 in 31 are carriers (heterozygous) If both parents are carriers, the child has a 1 in 4 chance of inheriting two mutated genes: pedigree analysis, reveals inheritance patterns in families, make predictions/probabilities of, affected individual, carrier. X-linked traits: white eyed fly: identified by t. h. Morgan: different pattern of inheritance in reciprocal crosses, modes of inheritance, basic mendelian rules apply for determining genotypes but expression as phenotype will chance. 10-27-17: double par on pedigree = autosomal, autosomal presents itself in relatedness. 2n-2 (44 chromosomes: monosomy: loss of a single chromosome. 2n-1 (45: trisomy: gain of a single chromosome.

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