PSB2000 Brain Plasticity.docx

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PSB 2000
Stacey Mc Callister

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Brain Plasticity 1. Brain Damage Causes a. Tumor b. Toxic substances c. Degenerative disease d. Most common cause in young people i. Closed head injury 1. Sharp blow to head resulting from an accident, assault, or other force that doesn’t actually puncture the brain a. Mild  common, no lasting damage b. Severe  damage i. Rotational forces: brain hits skull ii. Blood clots: interrupt blood flow to brain e. Most common cause in old people i. Stroke – temporary loss of blood flow to the brain 1. Types: a. Ischemia – results from a blood clot or obstruction of an artery i. Neurons lose oxygen and glucose supply ii. Most common b. Hemorrhage – result from a ruptured artery i. Neurons flooded with excess blood, calcium, oxygen, and other chemicals ii. Less frequent 2. Ischemia and hemorrhage  edema and excess sodium  triggers glutamate release a. Overstimulation of neurons i. Sodium and other ions enter neuron faster than they can be removed, blocks metabolism in mitochondria 1. Kills neurons b. Edema – accumulation of fluid in the brain i. Increased pressure on brain, increases
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