ENGR 100 Lecture Notes - Lecture 8: Biomedical Engineering, Design Matrix, Hexane
Document Summary
Spring 2019 biological considerations: biocompatibility, inducing inflammation, short, medium and long term changes, lectrical safety, skin contact, bioburden. Risk table and design concept table (due 29th april) Culmanns crane presented by wolff in his 1870"s paper in virchow archiv. Optimal bone structure recognised by an engineer (karl cullman. Cancellous bone observed to occur along principal stress line. Julius wolff articulated the relationship in mathematical terms. Iterating to identify critical network of ideas. Ranking final design iteration-design history and evo. Formalised v&v (final test plan) validation (final total solution)- verification (checking if the requirements were taken) Changes with time (configuration)- implant too stiff sitting uncomfortably creating stiff mobile bearing (time is critical when considering design) Hexane based rubber- not biocompatible (feed the properties in a design matrix) check how we have mapped the risks and requirements for the concept series of changes in design knee prosthesis. Capsula joint (fully connected with gap between surfaces)
