BIOL 117 Lecture Notes - Lecture 24: Inbreeding Depression, Mutation, Aneuploidy

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20 Feb 2017
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Three important statements: inheritance does not cause evolution, evolution is populational, and is an extension of mendelian expectations about the outcomes of genetic crosses, we can use hardy-weinberg equilibrium as a null model to detect evolution. Hardy-weinberg: p+q = 1, p^2 + 2pq + q^2 = 1. When alleles are transmitted, doesn"t change frequencies. Inbreeding depression: concentration of loss of function alleles, reduced heterozygocity. Gene ow: moment of alleles between populations. When individuals leave on population and join another: tends to homogenize populations. Texas and florida panthers - positive gene ow: ex. Wild vs captive silver headed trout - negative gene ow. Mutation: any permanent change in an organism"s dna, a modi cation in a cell"s info archive, a change in its genotype, mutation creates new alleles, source of genetic variation. Mutation: random in respect to tness, provides raw material for evolution but by itself is not a very powerful body of change.

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