APPH 1040 Lecture 10: Introduction to infectious disease part

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The human body must defend itself against unwelcome intruders. It must also deal with abnormal body cells, which, in some cases, may develop into cancer. Two major kinds of defense have evolved to counter such threats. External barriers: acid mantle of skin, keratin, mucus intact skin epidermis. Intact mucous membranes: nasal hairs, cilia, gastric juice, acid mantle of vagina, urine. Infectious disease: any infection caused by microbes or parasites. Communicable disease: infection transmitted from persons or animals to other persons. Disease: changes in individuals that cause their health their health parameters to fall outside the range of normal. Iatrogenic: inadvertent medically induced effects causing disease or complication. Flys: pyrogens - secreted by macrophages and signal the body to increase temperature; high body temperature inhibits microbial multiplication and enhances body repair processes. Fever; temperature in the mouth (oral) is at or over 37. 7 c (99. 9 f.

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