BIOL 3755 Lecture Notes - Lecture 4: Reactive Oxygen Species, Protein Structure, Phagosome
Document Summary
Quiz 1 tuesday or thursday; mc and short answer. Will give hypothetical situation how to cure certain disease. Chapter 3 cellular structure, proteins, and metabolic pathways. Cells: functional unit of living organisms, highly organized and complex, acquire and use energy, carry out specialized functions and controls numerous reactions. Involved in all physiological processes, from cell signaling to tissue remodeling to organ function: dna rna through transcription protein through translation. Proteases can come into ribosome and cut polypeptides to create certain proteins. Tfs can bind to different regions within different genes and either suppress or enhance gene transcription. Important regulators of gene expression: may carry out both gene inhibition and gene activation, about 25 to 40% of coding genes have overlapping antisense transcription so impact of lncrnas on gene regulation is not to be underestimated. Proteolytic cross talking: 99% go to proteasome for degradation, lysosomal degradation, chaperones can tag proteins and take protein directly to lysosome, microautophagy.
