BIOL 2107K Lecture Notes - Lecture 12: Sister Chromatids, Spindle Apparatus, Nuclear Membrane
Document Summary
Cell division ch 11 (cid:862)the (cid:272)o(cid:374)ti(cid:374)uity of life is (cid:271)ased o(cid:374) the reprodu(cid:272)tio(cid:374) of (cid:272)ells, or (cid:272)ell divisio(cid:374). (cid:863) Genetic regulation includes ftsz ring to constrict and divide cells. Phosphoryation of target proteins regulate and coordinate movement through the cell cycle. Cyclins are transient, in their absence, the cycle can stall p53, protein kinase. Tumor suppressor genes and other cancer-related genes p53 = tsg (cid:858)the guardia(cid:374)(cid:859) typically deactivated in cancerous cells. Once mutated to oncogenes loss of cell cycle controls. When good cells go bad (or have lived/divided for long), apoptosis. Behavior of chromosomes in meiosis is key to sexual reproduction and genetics! Cross-dressing or crossing-over: sex testing of women athletes. Maureen knabb, department of biology, west chester university, and joan sharp, biological sciences, Chromosomes after division are composed of 2 chromatids. Position of centromere metacentric: centromere in middle acrocentric: centromere at extreme end telocentric: centromere near end.
