BIOL 2107K Lecture Notes - Lecture 11: Microtubule, Chromatin, Necrosis

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21 Jul 2016
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Study guide chapter 11 cell cycle and cell division. Reproduction of the entire single-celled organism (prokaryotes) Unicellular- will divide or not divide in respond to conditions in the environment (environmental conditions and nutrient concentrations) Multicellular- will divide if something is needed by the organism. Bacteria- 1 chromosome, single long dna molecule with proteins bound to it; circular chromosome. Eukaryotic- have many chromosomes; the newly replicated chromosomes are closely associated with each other (also called sister chromatids) S phase- dna is replicated; each chromosome is duplicated and thereafter consists of two sister chromatids joined together and awaiting segregation into two new cells. M phase- mitosis and cytokinesis; nuclear division occurs during mitosis and cell division (cytokinesis) occurs at the end of the m phase. Cyclin-dependent kinases or cdk- not active by themselves; need to activated by binding to a second type of protein, cyclin; allosteric regulation- activates the cdk by altering its shape and exposing its active site.

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