BIOL 2120K Lecture Notes - Lecture 9: Erythropoiesis, Vasospasm, Histamine
Document Summary
Albumin response for colloid osmotic pressure - final question. Blood components - plasma (55%), buffy coat (<1%), and erythrocytes (44%) Myeloid stem cells (multipotent stem cell) can give rise to a number of csf cells. Erythropoietin (hormone) that sets off erythropoiesis - red blood cell production. Just a sack of protein; so it is temporary. Thrombopoietin makes megakaryoblast --> megakaryoyte that makes platelets. Granulocyte colony stimulating factor or monocyte colony stimulating factor. Megakaryocytes cannot enter blood, but they attach to blood vessels and platelets snap off. Erythrocytes are bi-concave shaped (compression in the middle). About the size of a capillary, move single file through them. Deoxyhemoglobin: hb after oxygen diffuses into tissues (reduced hb). Kidney will produce erythropoietin is oxygen levels are low. When oxygen levels are okay (negative stimulus) the kidney will stop producing erythropoietin (hormone). When heme breaks down, it is a green color. Expelled in feces and urine (brown and yellow).
