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Lecture 7

BMS 212 Lecture Notes - Lecture 7: Endoplasmic Reticulum, Golgi Apparatus, Nuclear Membrane

3 pages99 viewsFall 2016

Biomedical Sciences
Course Code
BMS 212
Aaron Baxter

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Viral Structure, Classification and Growth of Viruses
Historical contributors:
1. Charles Chamberland- advanced the ability to create sterile items and developed bacterial
filters and autoclaves
2. Beijerinck and Ivanowski- Used Chamberlands bacterial filters to establish the existence
of the Tobacco Mosaic Virus the virus fell through the filter
- Called these entities Contagium Vivum Fluidium
- Integral in the establishment of virology
I. Viruses vs. Life
Criteria for life:
1. Growth- the ability to increase in size
2. Reproduction- the ability to increase in number
3. Responsiveness- change in internal/external properties in response to the environment
4. Metabolism- taking in nutrients, reactions to create energy that’s stimulate growth
*Viruses do not meet criteria 1 or 4, so they are defined as “particles”*
II. Structure
A. Size
B. Structures in viruses
1. 3 general classifications of viruses
1. Icosahedron
2. Helical
3. Complex
1. Naked
2. Enveloped
2. Common structure to all viruses
a. Central core
- Nucleic acid:
o DNA or RNA
o Single or double stranded
o Circular or linear
o Segmented or non-segmented
- Small number of genes
o i.e. humans have 30,000, hepatitis B has 4
- Function is very directed: replication of outer material and genetic
material, regulation of the host, and packaging
i. some viruses also carry a few very specific enzymes
a. Polymerases: synthesize viral specific DNA or RNA
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