SPHR 2106 Lecture Notes - Lecture 11: Multiple Sclerosis, Edema, Wallerian Degeneration

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If axon hillock recognizes that threshold has been reached, further opens the gates, pushes to become above zero. Channels close and inside becomes more negative and goes below resting potential. During refractory period: inside of neuron is more negative below threshold, another action potential cannot be generated. Myelinated axon: action potentail jumps from one node to another. Unmyelinated axon: action potential has to go through every single gate in axon. Telodendron: terminal bouton filled with neurotransmitters contained in vesicles. Outer end of terminal bouton, released into synaptic cleft. Postsynaptic neuron: specialized receptor sites for certain types for neurotransmitter substances. Each neuron has only one kind of neurotransmitter substance depends on receptor sites. Excitatory: depolarization, more positive ions flow into postsynaptic cell. When action potential gets to the end, it makes the terminal bouton secrete neurotransmitter substances: either excitatory/inhibitory postsynaptic potential. Excitation causes action at the other end of the synapse:

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