Class Notes (838,343)
United States (325,349)
Robert Lue (13)
Lecture 14

Lecture 14 – Transcription.docx

1 Page
45 Views
Unlock Document

Department
Life Sciences
Course
Life Sciences 1a
Professor
Robert Lue
Semester
Fall

Description
Oct 17 – Transcription ­ 5’ methyl group irrelevant to base pairing ­ uracil is recognized as foreign in DNA and replaced with cytosine to prevent  mutation effects ­ if DNA had uracil, cytosines that had undergone deamination could not be  recognized ­ doesn’t matter for RNA because RNA is not genetic material  ­ no lagging strand in transcription  ­ promoters tell RNA polymerase where to start transcribing  ­ upstream of transcription start site (+1) ­ refer to non­template strand  ­ no individual promoter is perfect match for platonic ideal  ▯TTGACA most  common in statistical analysis  ­ sigma contacts and recognizes ­35 and ­10 sequences, forms closed complex then  open complex then initiation then elongation then termination  ­ eukaryotic RNA polymerase not intrinsically capa
More Less

Related notes for Life Sciences 1a

Log In


OR

Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


OR

By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.


Submit