BIOS-1113 Lecture Notes - Lecture 17: Bone Marrow, Dna Replication, Cell Growth

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Stages of interphase: g1 phase, s phase, g2 phase. This is the on dividing stage of cell cycle cell is involved in dna replication and growth. Phase where cell is most vulnerable to genetic mutation. Neurons (nerve cells, b/c of lack of centrioles) Cells that do not divide, but can when introduced to stimulus: liver cells, lymphocytes. Cells of intestinal lining (whole gi tract, colon cancer) Bone marrow cells (leukemia) these are all subject to destruction! Chromosome dark, threadlike body in the nucleus containing genetic information. Unit of dana it takes to construct one protein it"s all the nucleic acid sequences coded for that protein. Number and type of chromosome an individual has. Serves as organizing center for mitotic spindle! cylindrically shaped organelle composed of 9 triplets of microtubules. Mitotic spindle guides chromosome as they move through a cell. Stages of mitosis: prophase, metaphase, anaphase, telephase. The nuclear membrane disappears and the chromosome becomes more condensed.

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