BIOL10800 Lecture Notes - Lecture 5: Posterior Pituitary, Anterior Pituitary, Autonomic Nervous System
Document Summary
Cell surface contains receptors specific for various ligands. Binding of a native ligand (drug/other things) to a receptor initiates a cellular pathway coupling the receptor to the cell response. Cell can respond by increasing/decreasing in activity: ex: autonomic nervous system. Cells can be capable of multiple responses triggered by different ligands: ex: secretory cells of glands, different pathways in cells lead to different responses from binding. Blocks receptor from doing its normal job + binding: blocking response the receptor would have triggered, ex: acid secreting cells are blocked by antagonists. Ulcer that may be being caused is healed. Antagonist that blocks inhibited receptor will cause cell to increase in response. Inhibition: antagonist that blocks excited receptor will cause cell to decrease in response: inhibition can be paradoxical. Endocrine system is compromised of 2 important cns (central nervous system) elements: hypothalamus, posterior pituitary. 8 principle glands: anterior pituitary, pineal, parathyroid, adrenal (keeps stress down, tests/ovary, pancreas (insulin)