AN S 345 Lecture Notes - Lecture 25: Antigen, Blood Proteins, Ubiquitin

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Pro-inflammatory cytokines important for directing traffic. The best immune response an animal can have is a fast one and one that does not require outside sources and can return to normal homeostasis without intervention. Respiration oxidative burst is controlled by the enzyme nadph oxidase which is also related to the other metabolic pathways. Developed during lifetime as an adaptation to infection. Lymphocytes rearrange their antigen receptors to gain sensitivity to specific pathogens. Delayed response compared to the innate system. B and t cells are associated with memory of the pathogen. Key concept: vaccinations require both adaptive and innate systems to be. Innate immune responses do not have memory of the pathogen activated at some point. Develops upon exposure to various antigens and the host builds a defense that is specific to that antigen. More than 96 hours are needed for activation/response.

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