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Lecture 12

CEUS-R 310 Lecture Notes - Lecture 12: Veterinary Virology, Zoonosis, Coronavirus

2 pages36 viewsFall 2015

Department
Central Eurasian Studies
Course Code
CEUS-R 310
Professor
Elisabeth Lloyd
Lecture
12

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12/2/15: Humans and Diseases
Animals and human health
o disease
o biological anthropologist
o molecular genetics of human viruses
diseases and human evolution
o role of viral parasites in human evolution
o decline of less resistant populations- biologically and culturally
structure of adenovirus
gene therapy- novel cancer therapy
relationships between human and animal viruses
o some with long histories
o some more recent
Africa
domesticated animals- commensal species- chicken and monkey
examples of virus families that co-evolved with human and animals
o hantavirus (rodents)
o common cold (cattle, pigs, rodents, cats, chicken, apes)
o West Nile (mosquitoes)
disease vector- how transmitted (mosquitoes)
disease reservoir-host (birds)
o influenza-flu (pigs, horses, birds)
different kinds of the flu that can affect animals and humans
differently
swine flu- pigs
avian flu- chickens
o HIV/ SIV (primates)
o rabies (many animals, from bats, animals can pass it on to other animals
then animals can give it to humans)
o occasional cross-species transmissions- often happens in crowded
conditions; dense populations
o zoonotic infections- pathogens transmitted from nonhuman to human
animals
o anthropozoonotic infections- pathogens transmitted from human to
nonhuman animals
scientific case studies history of events of diseases that occurred
o scientists confirm virus as cause of SAR (severe acute respiratory
syndrome)
coronavirus
zoonotic source
from animals to humans in China
pigs, chickens, civet cats for sale in food markets
experiments with monkeys confirmed this virus (able to save
people by doing experiments on animals that have similarities and
genetics)
o SARS- worldwide outbreak 2002-2004
>8,000 confirmed cases
774 deaths in 29 countries
started in one area, then moved in many other areas because of
global transportation
causes of outbreak-
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