PSY-P 346 Lecture Notes - Lecture 1: Substantia Nigra, Parasympathetic Nervous System, Septal Nuclei
14 Nov 2017
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Document Summary
Thalamus releases less glutamate to the cortex. Characterized by loss of dopaminergic neurons in substantia nigra. Direct path=no inhibition of snr, increased gaba, more inhibition on thalamus, less. Indirect= results in less glutamate to thalamus; less excitation of cortex. A genetic autosomal dominant neurodegenerative disease characterized by cognitive, More cag repeats will result in earlier disease onset. Issue with indirect pathway with no real inhibition. Need to be able to terminate response. Action potentials are started and the neurotransmitters sist in the cleft, need a way to get. Neurotransmitter could get taken up by transporter or broken down by enzyme. Point to point discrimination; very direct; signal to specific location in the brain. Diffuse modulatory systems; the whole brain can receive the signal; very broad. Focussed: good when subtleties are desired; point to point. Integrates somatic and visceral responses with needs. Peri does communication with pituitary; regulates hormones. Neurosecretory neurons extend toward stalk of pituitary gland.
