BIOL 104 Lecture Notes - Lecture 1: Human Genetic Variation, Axon Terminal, Single-Nucleotide Polymorphism
Document Summary
Autism is associated with social impairment: do not respond to their names, avoid eye contact, may not understand how to play/engage with other children, no speech/awkward speech, delated speech/language skills. Autism is associated with repetitive behaviors: repetitive speech, repetitive movements, thrive on routine (can be a detriment, obsessively interested in a topic (can be a detriment) There has been a rise in autism diagnosis: rate of autism diagnosis among children is roughly 1/100. Possible factors that contribute to the rise in diagnosis: broader diagnostics, awareness, parents are waiting longer to have children. 36%-95% likely the other twin has autism: the risk, for parents, of having a second child with autism increases, rate goes up with the age of parents, boys are more likely to have autism. Genome-wide association studies (gwas: a research technique to identify genetic polymorphisms and to understand how they differ between large populations, polymorphisms (cid:894)(cid:862)(cid:373)a(cid:374)y for(cid:373)s(cid:863)(cid:895) are t(cid:449)o or (cid:373)ore ge(cid:374)eti(cid:272) differe(cid:374)(cid:272)es (cid:449)ithi(cid:374) or (cid:271)et(cid:449)ee(cid:374) populations.
