BIOL 104 Lecture Notes - Lecture 11: Mitosis, Independent Community And Health Concern, Trisomy
Document Summary
Biol 106 human genetics and health dr. major. Removal of the aer + fgf = growth. The development of a complex structure like the human arm is an excellent model for understanding how spatial-specific gene expression can control organized growth and patterning. When two cells want to communicate, one cell releases a signaling factor (often a protein) that binds to a receptor on the surface of the other cell. Activation of the receptor at the cell membrane activates a cascade of events in the cytoplasm that amplifies the signal (think of a game of telephone where one person tells two and those two people tell two people . Finally, the signal enters the nucleus where genes are turned on/off. This is how cells in the embryo know what to do. We discussed two signals in the developing limb. The limb bud extends from the sides of the embryo and the outer rim of tissue is called the apical.
