BIOL 104 Lecture Notes - Lecture 10: Morphogen, Alkaloid, Cyclopamine
Document Summary
The noto(cid:272)hord (cid:862)patterns(cid:863) the neural tu(cid:271)e: neural tube, notochord. Neurons across the d/v axis of the neural tube are different: dorsal (reds, ventral (blues) Neural organization must be specified across the d/v axis: spinal neurons in the dorsal region receive input from sensory neurons. Interneurons relay information between sensory and motor neurons in the middle. Cyclopamine is a natural alkaloid isolated from the corn lily, veratrum californicum. Sonic hedgehog acts as a morphogen (form giver) Diffusible molecules that can determined cell fate by their concentrations.
