AS.280.335 Lecture Notes - Lecture 3: Enterococcus, Temporality, Aflatoxin
13 Sep 2016
School
Department
Course
Professor
Document Summary
Epidemiology studies the broad relationship/association between exposure and its related health outcome (disease) Exposure-response relationship between frequency/intensity/duration of exposure and frequency of health outcome is positive (upward sloping) if adverse or negative (downward sloping) if protective: i. e. frequency of health outcome is a linear function of frequency of exposure. In order to get exposure-response association, use epidemiologic study designs: experimental design (randomized controlled trials) From the population, you apply exclusion criteria and derive a sample. Randomize subjects in a study to either get a treatment/exposure or not in an attempt to distribute both measurable and unmeasurable factors (i. e. age, race/ethnicity, sex, etc. ) equally between the two groups. The hope is that this creates identical conditions between the two groups (unbiased way to look at the effective exposure or treatment) 1. 0 is the null value for odds ratio no effect on relationship between exposure factor and the outcome. Values in brackets are confidence intervals lower and upper bounds.
