BIO 370 Lecture Notes - Lecture 6: Muscarinic Acetylcholine Receptor, Alpha Particle, Skeletal Muscle
Document Summary
Graded and action potentials (figure 5-4 & 6-1) Aps are a special case; they are large and quick. Chapter 6 slides: graded and action potentials. Action potential is special case of graded. Graded responses happen in cell body somas/dendrites and terminals. An action potential response is best suited for an axon, something special is happening in axon. (positive feedback that we keep stimulating aps: electrotonic transmission of graded signal (figure 6 3) Positive change in graph (stimulus caused), we have recording electrodes all along the line. If sub threshold we detect a change in further time point. Graded potentials move, like movement of ions, high [ ] to low [ ]. (diffusion). Electrotonic transmission is like diffusion of ions: aps are short lived . We expect to see same magnitude (positive hodgkins cycle) By positive feedback cycle stimulating previously active closed vgics: regenerative transmission of action potentials (figure 6-4a)