BSCI 10001 Lecture Notes - Lecture 24: Pribnow Box, Tata Box, Lac Operon

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Remember we said that in the case of bacteria, the amount or activity of any protein found inside a bacterial cell could be governed in any of 3 ways: In the case of animal cells, there is also control at the level of: You may remember that bacterial promoters typically consist of a pribnow box (-10 region) and a sequence called the -35 region : In other cases (eg, the lac operon) a dna sequence that binds a positive control element like the cap protein is required. For these genes, the promoter sequence is suboptimal, and binding of the cap protein is necessary to recruit rna polymerase. Eukaryotic promoters have a sequence that sort of resembles the pribnow box of prokaryotic promoters, but it is located -25 to -35 to the transcription start site. After tfiid binds to the tata box and bends the dna, a set of additional proteins (tfiia,

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