BIOL 150 Lecture Notes - Lecture 17: Citric Acid Cycle, Oxidative Phosphorylation, Succinic Acid
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1. Choose the TWO correct statements describing the citrate cycle.
ATP is an indirect product of the citric acid cycle | |
Acetyl CoA can increase the pool of citric acid cycle intermediates | |
Fatty acids can increase the pool of citric acid cycle intermediates | |
ADP inhibits α-ketoglutarate dehydrogenase | |
The pool of mitochondrial oxaloacetate can be increased by pyruvate | |
All enzymes of the citric acid cycle are found soluble and free in the mitochondrial matrix |
2.Which molecule in the net reaction of the citrate cycle contributes to the inhibition of pyruvate dehydrogenase?
NADH | |
H+ | |
H2O | |
FAD |
3. How would a high NADH to NAD+ ratio be expected to affect the pyruvate dehydrogenase reaction?
The E1 subunit is phosphorylated by pyruvate dehydrogenase kinase, and the catalytic activity of pyruvate dehydrogenase decreases. | |
The last step of the pyruvate dehydrogenase reaction is blocked, resulting in a decrease in activity. | |
The pyruvate dehydrogenase phosphatase-1 enzyme would increase, resulting in pyruvate dehydrogenase activation at an accelerated rate. | |
The pyruvate dehydrogenase kinase enzyme activity would increase, resulting in an increase in pyruvate dehydrogenase activity. |
force times distance |
Question 48
Soccer (assuming field player) is a sport which is 90% aerobic.
True
False
Question 50
Glucose is necessary for fatty acid oxidation because...
its derivative, pyruvate, is condensated with carbonic acid to form oxaloacetate, which in turn is a necessary carbon compound in the citric acid cycle | ||
it is needed to convert fatty acids to fatty acyl-CoA which in turn is oxidized to acetyl CoA | ||
glucose is decarboxylated into cytochrome oxidase which is a necessary intermediate in the citric acid cycle | ||
its derivative, acetyl CoA, is condensated with carbonic acid to form lactase, which in turn is a necessary carbon compound in the citric acid cycle |
Question 51
In aerobic ATP production, the role of oxygen is to...
to keep the electron transport chain operational | ||
to accept electrons from the 3rd cytochrome and thereby oxidizing it so it can accept new electrons | ||
act as a oxidizing agent by accepting electrons from the electron transport chain and combining with hydrogen ions (protons) | ||
all of the above |
Question 52
The primary purpose of the citric acid cycle is...
aerobic glycolysis | ||||||||||||||
gluconeogenesis using lactate | ||||||||||||||
the decarboxylation of carbon compounds to produce NADH. | ||||||||||||||
the shuttling of hydrogen ions through the inner mitochondrial membrane Question 55 Which of the following is the best predictor of marathon running performance?
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