BIOL 150 Lecture Notes - Lecture 22: Intermediate Filament, Cilium, Filopodia
Document Summary
Biol 150 principles of molecular & cellular biology. We looked at the second major set of rigid filaments that determine the shape of cells, the microtubules. These are built of dimers of the protein tubulin, and have a minus (-) end that does not change much, and a plus end that grows steadily or shrinks very rapidly (which is called. The minus end of most microtubules is located at the centromere (mtoc or. The minus end is anchored by several proteins, including the anchoring gamma-tubulin ( -tubulin) discovered by ku professor berl. The plus ends grow out towards the edge of the cell. We saw a short movie of this process. In neurons, microtubules grow out through to stabilize the long narrow projection (the. Axon ) that reaches out to the target of that neuron, which could be up to several meters away.
