JAPAN 2 Lecture Notes - Lecture 30: Vascular Endothelial Growth Factor, Bevacizumab, Glioma
Document Summary
A tumor is a mass of cells whose growth is uncontrolled and that serves no useful function. Encapsulated tumors grow within their own membrane benign tumor (e. g. meningiomas). Infiltrating tumors infiltrate the surrounding tissue and cannot be cut out completely malignant tumor. The missed cells can produce a new tumor (e. g. gliomas). A metastasizing tumor will shed cells, which then travel through the bloodstream, lodge in capillaries, and serve as seeds for the growth of new tumors in different locations of the body. Tumors damage the brain tissue by two means: compression and infiltration. The compression can directly destroy brain tissue, or indirectly by blocking the flow of cerebrospinal fluid and causing hydrocephalus. Chemotherapy: administration of a drug that causes rapidly dividing cells to die by interfering with their dna replication. Bevacizumab: a drug that inhibits angiogenesis, the growth of new blood vessels.
