MATH 190 Lecture Notes - Lecture 7: The Fluid, Cytoskeleton, Resting Potential
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When a cell is not generating impulses it is said to be at rest. In the resting neuron, the cytosol along the inside surface of the membrane has a negative electrical charge compared to the outside. This difference in electrical charge across the membrane is called the resting membrane potential. The resting membrane potential of a typical neuron is about -65 mili volts. The membrane potential is the voltage across the membrane (vm). Depolarization: moving away from the negative charge( so from -65 to -17 f. e. ) The three main players in creating the resting potential are: the salty fluids on the inside of the membrane, membrane itself, proteins that span the membrane. 1. the fluid inside the neuron is called the intracellular fluid or cytosol. Ions can dissolve in water because water-molecules are polar ( one side is positive, other side is negative). Ions with a positive charge are called cations and ions with a negative charge are called anions.
